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Principles and functions of condensate modifying drugs

Biomolecular condensates are compartmentalized communities of biomolecules, which unlike traditional organelles, are not enclosed by membranes. Condensates play roles in diverse cellular processes, are dysfunctional in many disease states, and are often enriched in classically “undruggable” targets....

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Detalles Bibliográficos
Autores principales: Patel, Avinash, Mitrea, Diana, Namasivayam, Vigneshwaran, Murcko, Mark A., Wagner, Michael, Klein, Isaac A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9725174/
https://www.ncbi.nlm.nih.gov/pubmed/36483537
http://dx.doi.org/10.3389/fmolb.2022.1007744