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Principles and functions of condensate modifying drugs
Biomolecular condensates are compartmentalized communities of biomolecules, which unlike traditional organelles, are not enclosed by membranes. Condensates play roles in diverse cellular processes, are dysfunctional in many disease states, and are often enriched in classically “undruggable” targets....
Autores principales: | Patel, Avinash, Mitrea, Diana, Namasivayam, Vigneshwaran, Murcko, Mark A., Wagner, Michael, Klein, Isaac A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9725174/ https://www.ncbi.nlm.nih.gov/pubmed/36483537 http://dx.doi.org/10.3389/fmolb.2022.1007744 |
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