Cargando…

The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis

Tafenoquine is a newly licensed antimalarial drug for the radical cure of Plasmodium vivax malaria. The mechanism of action and optimal dosing are uncertain. We pooled individual data from 1102 patients and 72 healthy volunteers studied in the pre-registration trials. We show that tafenoquine dose i...

Descripción completa

Detalles Bibliográficos
Autores principales: Watson, James A, Commons, Robert J, Tarning, Joel, Simpson, Julie A, Llanos Cuentas, Alejandro, Lacerda, Marcus VG, Green, Justin A, Koh, Gavin CKW, Chu, Cindy S, Nosten, François H, Price, Richard N, Day, Nicholas PJ, White, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9725750/
https://www.ncbi.nlm.nih.gov/pubmed/36472067
http://dx.doi.org/10.7554/eLife.83433