Ashwagandha-loaded nanocapsules improved the behavioral alterations, and blocked MAPK and induced Nrf2 signaling pathways in a hepatic encephalopathy rat model

Ashwagandha (ASH), a vital herb in Ayurvedic medicine, demonstrated potent preclinical hepato- and neuroprotective effects. However, its efficacy is limited due to low oral bioavailability. Accordingly, we encapsulated ASH extract in chitosan–alginate bipolymeric nanocapsules (ASH-BPNCs) to enhance...

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Detalles Bibliográficos
Autores principales: Khalil, Heba M. A., Khalil, Islam A., Al-Mokaddem, Asmaa K., Hassan, Marwa, El-Shiekh, Riham A., Eliwa, Hesham A., Tawfek, Azza M., El-Maadawy, Walaa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726678/
https://www.ncbi.nlm.nih.gov/pubmed/35672652
http://dx.doi.org/10.1007/s13346-022-01181-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726678/
https://www.ncbi.nlm.nih.gov/pubmed/35672652
http://dx.doi.org/10.1007/s13346-022-01181-y

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