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Interaction between human leukocyte antigen (HLA-C) and killer cell Ig-like receptors (KIR2DL) inhibits the cytotoxicity of natural killer cells in patients with hepatoblastoma

BACKGROUND: Hepatoblastoma (HB) is the most common liver malignancy in childhood with poor prognosis and lack of effective therapeutic targets. Single-cell transcriptome sequencing technology has been widely used in the study of malignant tumors, which can understand the tumor microenvironment and t...

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Detalles Bibliográficos
Autores principales: Guo, Jing-Jie, Ye, Yong-Qin, Liu, Yi-Di, Wu, Wei-Fang, Mei, Qian-Qian, Zhang, Xi-Yun, Lao, Jing, Wang, Bin, Wang, Jian-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726742/
https://www.ncbi.nlm.nih.gov/pubmed/36507493
http://dx.doi.org/10.3389/fmed.2022.947729