Dexmedetomidine Restores Autophagic Flux, Modulates Associated microRNAs and the Cholinergic Anti-inflammatory Pathway upon LPS-Treatment in Rats

ABSTRACT: Infections and perioperative stress can lead to neuroinflammation, which in turn is linked to cognitive impairments such as postoperative delirium or postoperative cognitive dysfunctions. The α2-adrenoceptor agonist dexmedetomidine (DEX) prevents cognitive impairments and has organo-protec...

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Detalles Bibliográficos
Autores principales: Kho, Widuri, von Haefen, Clarissa, Paeschke, Nadine, Nasser, Fatme, Endesfelder, Stefanie, Sifringer, Marco, González-López, Adrián, Lanzke, Nadine, Spies, Claudia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726767/
https://www.ncbi.nlm.nih.gov/pubmed/34357471
http://dx.doi.org/10.1007/s11481-021-10003-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726767/
https://www.ncbi.nlm.nih.gov/pubmed/34357471
http://dx.doi.org/10.1007/s11481-021-10003-w

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