Chronotherapy based on modified-release hydrocortisone to restore the physiological cortisol diurnal rhythm

In this inspirational note, we describe the development of an endocrine chronotherapy to restore the physiological rhythm of the essential adrenal stress hormone, cortisol. The challenges included demonstrating the circadian rhythm of the drug target, creating a drug formulation that replicated that...

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Detalles Bibliográficos
Autores principales: Whitaker, Martin J., Huatan, Hiep, Ross, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Inspirational Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726814/
https://www.ncbi.nlm.nih.gov/pubmed/35618893
http://dx.doi.org/10.1007/s13346-022-01183-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726814/
https://www.ncbi.nlm.nih.gov/pubmed/35618893
http://dx.doi.org/10.1007/s13346-022-01183-w

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