Novel expression cassettes for increasing apolipoprotein AI transgene expression in vascular endothelial cells

Transduction of endothelial cells (EC) with a vector that expresses apolipoprotein A-I (APOAI) reduces atherosclerosis in arteries of fat-fed rabbits. However, the effects on atherosclerosis are partial and might be enhanced if APOAI expression could be increased. With a goal of developing an expres...

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Detalles Bibliográficos
Autores principales: Sethuraman, Meena, Dronadula, Nagadhara, Bi, Lianxiang, Wacker, Bradley K., Knight, Ethan, De Bleser, Pieter, Dichek, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726828/
https://www.ncbi.nlm.nih.gov/pubmed/36473901
http://dx.doi.org/10.1038/s41598-022-25333-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726828/
https://www.ncbi.nlm.nih.gov/pubmed/36473901
http://dx.doi.org/10.1038/s41598-022-25333-9

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