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Novel expression cassettes for increasing apolipoprotein AI transgene expression in vascular endothelial cells

Transduction of endothelial cells (EC) with a vector that expresses apolipoprotein A-I (APOAI) reduces atherosclerosis in arteries of fat-fed rabbits. However, the effects on atherosclerosis are partial and might be enhanced if APOAI expression could be increased. With a goal of developing an expres...

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Detalles Bibliográficos
Autores principales:	Sethuraman, Meena, Dronadula, Nagadhara, Bi, Lianxiang, Wacker, Bradley K., Knight, Ethan, De Bleser, Pieter, Dichek, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726828/ https://www.ncbi.nlm.nih.gov/pubmed/36473901 http://dx.doi.org/10.1038/s41598-022-25333-9

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