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Synthesis and in vitro antibacterial, antifungal, anti-proliferative activities of novel adamantane-containing thiazole compounds

A series of (Z)-N-(adamantan-1-yl)-3,4-diarylthiazol-2(3H)-imines (5a-r) was synthesized via condensation of 1-(adamantan-1-yl)-3-arylthioureas (3a-c) with various aryl bromomethyl ketones (4a-f). The structures of the synthesized compounds were characterized by (1)H NMR, (13)C NMR and by X-ray crys...

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Detalles Bibliográficos
Autores principales: Warda, Eman T., El-Ashmawy, Mahmoud B., Habib, El-Sayed E., Abdelbaky, Mohammed S. M., Garcia-Granda, Santiago, Thamotharan, Subbiah, El-Emam, Ali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726863/
https://www.ncbi.nlm.nih.gov/pubmed/36474013
http://dx.doi.org/10.1038/s41598-022-25390-0