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A metabolic associated fatty liver disease risk variant in MBOAT7 regulates toll like receptor induced outcomes
The breakdown of toll-like receptor (TLR) tolerance results in tissue damage, and hyperactivation of the TLRs and subsequent inflammatory consequences have been implicated as risk factors for more severe forms of disease and poor outcomes from various diseases including COVID-19 and metabolic (dysfu...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726889/ https://www.ncbi.nlm.nih.gov/pubmed/36473860 http://dx.doi.org/10.1038/s41467-022-35158-9 |