A metabolic associated fatty liver disease risk variant in MBOAT7 regulates toll like receptor induced outcomes

The breakdown of toll-like receptor (TLR) tolerance results in tissue damage, and hyperactivation of the TLRs and subsequent inflammatory consequences have been implicated as risk factors for more severe forms of disease and poor outcomes from various diseases including COVID-19 and metabolic (dysfu...

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Detalles Bibliográficos
Autores principales: Alharthi, Jawaher, Bayoumi, Ali, Thabet, Khaled, Pan, Ziyan, Gloss, Brian S., Latchoumanin, Olivier, Lundberg, Mischa, Twine, Natalie A., McLeod, Duncan, Alenizi, Shafi, Adams, Leon A., Weltman, Martin, Berg, Thomas, Liddle, Christopher, George, Jacob, Eslam, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726889/
https://www.ncbi.nlm.nih.gov/pubmed/36473860
http://dx.doi.org/10.1038/s41467-022-35158-9

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