Exploration of the effect of Celastrol on protein targets in nasopharyngeal carcinoma: Network pharmacology, molecular docking and experimental evaluations

Background: Celastrol, an important extract of Tripterygium wilfordii, shows strong antitumor activity in a variety of tumors including nasopharyngeal carcinoma (NPC). However, little is known about its targets in NPC. We aimed to screen the key gene targets of Celastrol in the treatment of NPC by m...

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Detalles Bibliográficos
Autores principales: Ling, Junjun, Huang, Yu, Sun, Zhen, Guo, Xiaopeng, Chang, Aoshuang, Pan, Jigang, Zhuo, Xianlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726908/
https://www.ncbi.nlm.nih.gov/pubmed/36506508
http://dx.doi.org/10.3389/fphar.2022.996728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726908/
https://www.ncbi.nlm.nih.gov/pubmed/36506508
http://dx.doi.org/10.3389/fphar.2022.996728

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