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Exploration of the effect of Celastrol on protein targets in nasopharyngeal carcinoma: Network pharmacology, molecular docking and experimental evaluations
Background: Celastrol, an important extract of Tripterygium wilfordii, shows strong antitumor activity in a variety of tumors including nasopharyngeal carcinoma (NPC). However, little is known about its targets in NPC. We aimed to screen the key gene targets of Celastrol in the treatment of NPC by m...
Autores principales: | Ling, Junjun, Huang, Yu, Sun, Zhen, Guo, Xiaopeng, Chang, Aoshuang, Pan, Jigang, Zhuo, Xianlu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726908/ https://www.ncbi.nlm.nih.gov/pubmed/36506508 http://dx.doi.org/10.3389/fphar.2022.996728 |
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