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The chromatin remodeler CHD6 promotes colorectal cancer development by regulating TMEM65-mediated mitochondrial dynamics via EGF and Wnt signaling

Chromodomain helicase DNA binding protein (CHD) family plays critical roles in regulating gene transcription. The family is linked to cancer disease, but the family member’s role in tumorigenesis remains largely unknown. Here, we report that CHD6 is highly expressed in colorectal cancer (CRC). CHD6...

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Detalles Bibliográficos
Autores principales: Zhang, Boyu, Liu, Qingxin, Wen, Weijie, Gao, Han, Wei, Wenxia, Tang, Aiwen, Qin, Baifu, Lyu, Haiwen, Meng, Xiangqi, Li, Kai, Jin, Huilin, Yu, Fenghai, Pan, Qihao, Lin, Junzhong, Lee, Mong-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727023/
https://www.ncbi.nlm.nih.gov/pubmed/36473865
http://dx.doi.org/10.1038/s41421-022-00478-z