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The anticancer effects of Metformin in the male germ tumor SEM-1 cell line are mediated by HMGA1

INTRODUCTION: Germ cell tumors (GCTs) are the most common type of cancer in young men. These tumors usually originate from the testis, but they can occasionally develop from extragonadal sites probably due to primordial germ cells (PGCs) migration errors. Cisplatin-based chemotherapy is usually effe...

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Detalles Bibliográficos
Autores principales: Salatino, Alessandro, Mirabelli, Maria, Chiefari, Eusebio, Greco, Marta, Di Vito, Anna, Bonapace, Giuseppe, Brunetti, Francesco S., Crocerossa, Fabio, Epstein, Alan L., Foti, Daniela P., Brunetti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727077/
https://www.ncbi.nlm.nih.gov/pubmed/36506071
http://dx.doi.org/10.3389/fendo.2022.1051988