Safety, pharmacokinetics, and pharmacodynamics of SHR7280, an oral gonadotropin-releasing hormone antagonist in healthy premenopausal women

Background: Treatment with gonadotropin-releasing hormone (GnRH) antagonists is a powerful strategy to suppress gonadotropin activity in women with sex hormone-dependent disorders. Herein, we provide the safety, pharmacokinetics (PK), and pharmacodynamics (PD) profiles of SHR7280, an oral non-peptid...

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Detalles Bibliográficos
Autores principales: Xu, Yi, Hu, Wei, Li, Jian, Jiang, Xin, Shi, Ping, Shen, Kai, Shen, Yu, Ma, Lingyu, Cao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727091/
https://www.ncbi.nlm.nih.gov/pubmed/36506562
http://dx.doi.org/10.3389/fphar.2022.1027648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727091/
https://www.ncbi.nlm.nih.gov/pubmed/36506562
http://dx.doi.org/10.3389/fphar.2022.1027648

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