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Steroid treatment suppresses the CD4(+) T-cell response to the third dose of mRNA COVID-19 vaccine in systemic autoimmune rheumatic disease patients

Prolonged steroid treatment has a suppressive effect on the immune system, however, its effect on the cellular response to mRNA vaccine is unknown. Here we assessed the impact of prolonged steroid treatment on the T-cell and humoral response to the SARS-CoV-2 spike (S) peptide following the third do...

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Detalles Bibliográficos
Autores principales: Maliah, Avishai, Parikh, Roma, Tayer-Shifman, Oshrat E., Kimhi, Oded, Gepstein, Raz, Halperin, Tami, Levy, Yair, Levy, Carmit, Pri-Paz Basson, Yael, Kivity, Shaye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727118/
https://www.ncbi.nlm.nih.gov/pubmed/36474011
http://dx.doi.org/10.1038/s41598-022-25642-z