The transmembrane domains mediate oligomerization of the human ZIP4 transporter in vivo

The human (h) ZIP4 is a plasma membrane transporter that functions to increase cytosolic zinc levels. hZIP4 encodes eight transmembrane domains and a large extracellular domain (ECD). This ECD is cleaved from the holo-transporter when cells are zinc-deficient. At the same time, mutations in the ECD...

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Detalles Bibliográficos
Autores principales: Liu, Yuting, Bafaro, Elizabeth M., Cowan, Ann E., Dempski, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727157/
https://www.ncbi.nlm.nih.gov/pubmed/36473915
http://dx.doi.org/10.1038/s41598-022-24782-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727157/
https://www.ncbi.nlm.nih.gov/pubmed/36473915
http://dx.doi.org/10.1038/s41598-022-24782-6

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