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Single-cell analysis reveals that Jinwu Gutong capsule attenuates the inflammatory activity of synovial cells in osteoarthritis by inhibiting AKR1C3

Jinwu Gutong capsule (JGC) is a traditional Chinese medicine formula for the treatment of osteoarthritis (OA). Synovitis is a typical pathological change in OA and promotes disease progression. Elucidating the therapeutic mechanism of JGC is crucial for the precise treatment of OA synovitis. In this...

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Detalles Bibliográficos
Autores principales: Guo, Junfeng, Tang, Chuyue, Shu, Zhao, Tang, Hong, Huang, Pan, Ye, Xiao, Liang, Taotao, Tang, Kanglai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727177/
https://www.ncbi.nlm.nih.gov/pubmed/36505054
http://dx.doi.org/10.3389/fphys.2022.1031996