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Persistent expression of NLRP3 in spinal microglia promotes development of lumbar disc degeneration
INTRODUCTION: Activated microglia play a critical role in the development of lumbar disc degeneration (LDD), which is a severe disease that causes neuropathic pain in affected people. Interleukin 1β (IL-1β) is a proinflammatory cytokine produced and secreted by activated microglia to induce the infl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727189/ https://www.ncbi.nlm.nih.gov/pubmed/36505450 http://dx.doi.org/10.3389/fimmu.2022.1064303 |