Metals-triggered compound CDPDP exhibits anti-arthritic behavior by downregulating the inflammatory cytokines, and modulating the oxidative storm in mice models with extensive ADMET, docking and simulation studies

Triggering through abiotic stress, including chemical triggers like heavy metals, is a new technique for drug discovery. In this research, the effect of heavy metal Nickel on actinobacteria Streptomyces sp. SH-1327 to obtain a stress-derived compound was firstly investigated. A new compound cyclo-(D...

Descripción completa

Detalles Bibliográficos
Autores principales: Hassan, Syed Shams ul, Abbas, Syed Qamar, Muhammad, Ishaq, Wu, Jia-Jia, Yan, Shi-Kai, Ali, Fawad, Majid, Muhammad, Jin, Hui-Zi, Bungau, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727203/
https://www.ncbi.nlm.nih.gov/pubmed/36506587
http://dx.doi.org/10.3389/fphar.2022.1053744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727203/
https://www.ncbi.nlm.nih.gov/pubmed/36506587
http://dx.doi.org/10.3389/fphar.2022.1053744

Ejemplares similares