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Type 1 interferon suppresses expression and glucocorticoid induction of glucocorticoid-induced leucine zipper (GILZ)

SLE is a systemic multi-organ autoimmune condition associated with reduced life expectancy and quality of life. Glucocorticoids (GC) are heavily relied on for SLE treatment but are associated with detrimental metabolic effects. Type 1 interferons (IFN) are central to SLE pathogenesis and may confer...

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Detalles Bibliográficos
Autores principales: Dankers, Wendy, Northcott, Melissa, Bennett, Taylah, D’Cruz, Akshay, Sherlock, Rochelle, Gearing, Linden J., Hertzog, Paul, Russ, Brendan, Miceli, Iolanda, Scheer, Sebastian, Fujishiro, Maki, Hayakawa, Kunihiro, Ikeda, Keigo, Morand, Eric F., Jones, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727222/
https://www.ncbi.nlm.nih.gov/pubmed/36505447
http://dx.doi.org/10.3389/fimmu.2022.1034880