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Hemoglobin induces inflammation through NF-kB signaling pathway and causes cell oxidative damage in grass carp (Ctenopharyngodon idella)

Hemolytic disease in grass carp (C. idella) leads to hemolysis in vivo, releasing damage-related molecular patterns (DAMPs) hemoglobin (Hb; which is rapidly oxidized to Hb-Fe(3+) and Hb-Fe(4+)) and generating a high level of reactive oxygen species (ROS) that cause oxidative damage. However, the eff...

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Detalles Bibliográficos
Autores principales: Tang, Ying, Yang, Shiyi, Yao, Minshan, Yang, Minxuan, Wei, Lixiang, Chen, Hong, Lin, Junyan, Huang, Yao, Lin, Li, Qin, Zhendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727223/
https://www.ncbi.nlm.nih.gov/pubmed/36505464
http://dx.doi.org/10.3389/fimmu.2022.1044299