AA147 ameliorates post-cardiac arrest cerebral ischemia/reperfusion injury through the co-regulation of the ATF6 and Nrf2 signaling pathways

Ischemia/reperfusion caused by cardiac arrest (CA) disturbs endoplasmic reticulum (ER) homeostasis and redox balance in neurons. AA147, originally developed as a pharmacologic activator of the activating transcription factor 6 (ATF6), can protect multiple tissues from ischemia/reperfusion injury (IR...

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Detalles Bibliográficos
Autores principales: Yuan, Zhu, Lu, Liping, Lian, Yingtao, Zhao, Yuanrui, Tang, Tingting, Xu, Song, Yao, Zhun, Yu, Zhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727236/
https://www.ncbi.nlm.nih.gov/pubmed/36506549
http://dx.doi.org/10.3389/fphar.2022.1028002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727236/
https://www.ncbi.nlm.nih.gov/pubmed/36506549
http://dx.doi.org/10.3389/fphar.2022.1028002

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