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One-pot double annulations to confer diastereoselective spirooxindolepyrrolothiazoles

A novel four-component reaction in one pot as an atom- and step-economic process was developed to synthesize diastereoselectively spirooxindolepyrrolothiazoles through sequential N,S-acetalation of aldehydes with cysteine and decarboxylative [3 + 2] cycloaddition with olefinic oxindoles. High synthe...

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Detalles Bibliográficos
Autores principales: Lu, Juan, Yao, Bin, Zhan, Desheng, Sun, Zhuo, Ji, Yun, Zhang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727273/
https://www.ncbi.nlm.nih.gov/pubmed/36530533
http://dx.doi.org/10.3762/bjoc.18.171