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A new route for the synthesis of 1-deazaguanine and 1-deazahypoxanthine

Imidazopyridines and pyrrolopyrimidines are an important class of compounds in medicinal chemistry. They can also be considered as deaza-modified purine nucleobases, and as such have attracted a lot of interest recently in the context of RNA atomic mutagenesis. In particular, for 1-deazaguanine (c(1...

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Detalles Bibliográficos
Autores principales: Bereiter, Raphael, Oberlechner, Marco, Micura, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727274/
https://www.ncbi.nlm.nih.gov/pubmed/36530531
http://dx.doi.org/10.3762/bjoc.18.172