Rhodium-catalyzed intramolecular reductive aldol-type cyclization: Application for the synthesis of a chiral necic acid lactone

A rhodium-catalyzed intramolecular reductive aldol-type cyclization is described to give β-hydroxylactones with high diastereoselectivities. The stereoselectivity of this cyclization is highly solvent dependent and can give syn- or anti-β-hydroxylactones with high diastereoselectivity. This methodol...

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Detalles Bibliográficos
Autores principales: Isoda, Motoyuki, Sato, Kazuyuki, Kameda, Kenta, Wakabayashi, Kana, Sato, Ryota, Minami, Hideki, Karuo, Yukiko, Tarui, Atsushi, Kawai, Kentaro, Omote, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727276/
https://www.ncbi.nlm.nih.gov/pubmed/36530534
http://dx.doi.org/10.3762/bjoc.18.176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727276/
https://www.ncbi.nlm.nih.gov/pubmed/36530534
http://dx.doi.org/10.3762/bjoc.18.176

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