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ZNF24 regulates the progression of KRAS mutant lung adenocarcinoma by promoting SLC7A5 translation

BACKGROUND: Clinical treatment of RAS mutant cancers is challenging because of the complexity of the Ras signaling pathway. SLC7A5 is a newly discovered downstream gene of the Ras signaling pathway, but the regulatory mechanism is unclear. We aimed to explore the molecular mechanism and role in KRAS...

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Detalles Bibliográficos
Autores principales: Jia, Daqi, Li, Leilei, Wang, Peng, Feng, Qiang, Pan, Xinyan, Lin, Peng, Song, Shuling, Yang, Lilin, Yang, Julun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727282/
https://www.ncbi.nlm.nih.gov/pubmed/36505791
http://dx.doi.org/10.3389/fonc.2022.1043177