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Deciphering the active constituents of Dabushen decoction of ameliorating osteoarthritis via PPARγ preservation by targeting DNMT1

Osteoarthritis (OA) is a multifactorial and chronic degenerative joint disease. Due to the adverse effects of currently used drugs, a safer and more effective therapy for treating OA is needed. Peroxisome proliferator-activated receptor-γ (PPARγ) is a key protein protecting cartilage. DNMT1-mediated...

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Detalles Bibliográficos
Autores principales: Qiu, Lu, Zhang, Min, Li, Chenghao, Hou, Yehu, Liu, Hao, Lin, Jia, Yao, Juan, Duan, Dong Zhu, Zhang, Yi Xi, Li, Mi, Li, Ya Ling, Wang, Peng, Li, Jin Tian, Jin, Xiao Jie, Liu, Yong Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727303/
https://www.ncbi.nlm.nih.gov/pubmed/36506533
http://dx.doi.org/10.3389/fphar.2022.993498