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Newly Substituted Anilino-Fluoroquinolones with Proliferation Inhibition Potential against a Panel of Cancer Cell Lines

BACKGROUND: From a chemistry point of view, we hypothesized that superlative dual cytotoxicity-radical scavenging bioefficacies of series 4 FQs correlate to their acidic groups and C8-C7 ethylene diamine Chelation Bridge. METHODOLOGY: Newly synthesized 16 lipophilic-acid chelating FQs have been scre...

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Detalles Bibliográficos
Autores principales: Salih, Mohammed Ameen Fouad, Al-Hiari, Yusuf, Kasabri, Violet, Darwish, Rula, Abumansour, Hamza, Bourghli, Laurance, Al Alawi, Sundus, Albashiti, Rabab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727339/
https://www.ncbi.nlm.nih.gov/pubmed/35901360
http://dx.doi.org/10.31557/APJCP.2022.23.7.2507