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Activation of metabotropic glutamate receptor 1 regulates hippocampal CA1 region excitability in rats with status epilepticus by suppressing the HCN1 channel
Dysregulation of hyperpolarization-activated cyclic nucleotide-gated cation (HCN) channels alters neuronal excitability. However, the role of HCN channels in status epilepticus is not fully understood. In this study, we established rat models of pentylenetetrazole-induced status epilepticus. We perf...
Autores principales: | Luo, Xiao-Dan, Xiang, Tao, Li, Si-Jun, Ma, Mei-Gang, Chen, Mei-Ling, Wu, Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727425/ https://www.ncbi.nlm.nih.gov/pubmed/36018183 http://dx.doi.org/10.4103/1673-5374.350206 |
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