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Platyconic acid A-induced PPM1A upregulation inhibits the proliferation, inflammation and extracellular matrix deposition of TGF-β1-induced lung fibroblasts

Platyconic acid A (PA), the active component of Platycodi radix-derived saponin, exerts ameliorating effects on liver fibrosis. Platycodon grandiflorum is used to treat lung disease. Therefore, the present study evaluated the effects of PA on pulmonary fibrosis. Transforming growth factor-β1 (TGF-β1...

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Detalles Bibliográficos
Autores principales: Su, Chengcheng, Tang, Yanfen, Wang, Cong, Huang, Haifeng, Hou, Haihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727587/
https://www.ncbi.nlm.nih.gov/pubmed/36069235
http://dx.doi.org/10.3892/mmr.2022.12845