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Platyconic acid A-induced PPM1A upregulation inhibits the proliferation, inflammation and extracellular matrix deposition of TGF-β1-induced lung fibroblasts
Platyconic acid A (PA), the active component of Platycodi radix-derived saponin, exerts ameliorating effects on liver fibrosis. Platycodon grandiflorum is used to treat lung disease. Therefore, the present study evaluated the effects of PA on pulmonary fibrosis. Transforming growth factor-β1 (TGF-β1...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727587/ https://www.ncbi.nlm.nih.gov/pubmed/36069235 http://dx.doi.org/10.3892/mmr.2022.12845 |