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LncRNA ZFAS1 contributes to osteosarcoma progression via miR-520b and miR-520e-mediated inhibition of RHOC signaling

OBJECTIVES: We examined the expression of Lnc-ZFAS1 in osteosarcoma and comprehensively evaluated its effects on osteosarcoma in vitro and vivo. Moreover, we revealed the regulatory mechanism between Lnc-ZFAS1 and miR-520b/miR-520e-mediated RHOC and provided a novel clue for ameliorating osteosarcom...

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Detalles Bibliográficos
Autores principales: Liu, Xiaofeng, Wang, Mingyang, Zhang, Liwen, Huang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727593/
https://www.ncbi.nlm.nih.gov/pubmed/36473367
http://dx.doi.org/10.1016/j.clinsp.2022.100143