Enhancement of T cell infiltration via tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors

Insufficient infiltration of T cells severely compromises the antitumor efficacy of adoptive cell therapy (ACT) against solid tumors. Here, we present a facile immune cell surface engineering strategy aiming to substantially enhance the anti-tumor efficacy of Th9-mediated ACT by rapidly identifying...

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Detalles Bibliográficos
Autores principales: Chen, Tao, Xue, Yucheng, Wang, Shengdong, Lu, Jinwei, Zhou, Hao, Zhang, Wenkan, Zhou, Zhiyi, Li, Binghao, Li, Yong, Wang, Zenan, Li, Changwei, Eloy, Yinwang, Sun, Hangxiang, Shen, Yihang, Diarra, Mohamed Diaty, Ge, Chang, Chai, Xupeng, Mou, Haochen, Lin, Peng, Yu, Xiaohua, Ye, Zhaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727594/
https://www.ncbi.nlm.nih.gov/pubmed/36514387
http://dx.doi.org/10.1016/j.bioactmat.2022.11.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727594/
https://www.ncbi.nlm.nih.gov/pubmed/36514387
http://dx.doi.org/10.1016/j.bioactmat.2022.11.022

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