Cargando…
Cannabinoid receptor 2 evolutionary gene loss makes parrots more susceptible to neuroinflammation
In vertebrates, cannabinoids modulate neuroimmune interactions through two cannabinoid receptors (CNRs) conservatively expressed in the brain (CNR1, syn. CB1) and in the periphery (CNR2, syn. CB2). Our comparative genomic analysis indicates several evolutionary losses in the CNR2 gene that is involv...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727682/ https://www.ncbi.nlm.nih.gov/pubmed/36475439 http://dx.doi.org/10.1098/rspb.2022.1941 |