Cannabinoid receptor 2 evolutionary gene loss makes parrots more susceptible to neuroinflammation

In vertebrates, cannabinoids modulate neuroimmune interactions through two cannabinoid receptors (CNRs) conservatively expressed in the brain (CNR1, syn. CB1) and in the periphery (CNR2, syn. CB2). Our comparative genomic analysis indicates several evolutionary losses in the CNR2 gene that is involv...

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Detalles Bibliográficos
Autores principales: Divín, Daniel, Goméz Samblas, Mercedes, Kuttiyarthu Veetil, Nithya, Voukali, Eleni, Świderská, Zuzana, Krajzingrová, Tereza, Těšický, Martin, Beneš, Vladimír, Elleder, Daniel, Bartoš, Oldřich, Vinkler, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Neuroscience and Cognition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727682/
https://www.ncbi.nlm.nih.gov/pubmed/36475439
http://dx.doi.org/10.1098/rspb.2022.1941

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