En1 and Lmx1b do not recapitulate embryonic dorsal-ventral limb patterning functions during mouse digit tip regeneration

The mouse digit tip regenerates following amputation. How the regenerate is patterned is unknown, but a long-standing hypothesis proposes developmental patterning mechanisms are re-used during regeneration. The digit tip bone exhibits dorsal-ventral (DV) polarity, so we focus on En1 and Lmx1b, two f...

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Detalles Bibliográficos
Autores principales: Johnson, Gemma L., Glasser, Morgan B., Charles, Julia F., Duryea, Jeffrey, Lehoczky, Jessica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727699/
https://www.ncbi.nlm.nih.gov/pubmed/36417876
http://dx.doi.org/10.1016/j.celrep.2022.111701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727699/
https://www.ncbi.nlm.nih.gov/pubmed/36417876
http://dx.doi.org/10.1016/j.celrep.2022.111701

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