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En1 and Lmx1b do not recapitulate embryonic dorsal-ventral limb patterning functions during mouse digit tip regeneration
The mouse digit tip regenerates following amputation. How the regenerate is patterned is unknown, but a long-standing hypothesis proposes developmental patterning mechanisms are re-used during regeneration. The digit tip bone exhibits dorsal-ventral (DV) polarity, so we focus on En1 and Lmx1b, two f...
Autores principales: | Johnson, Gemma L., Glasser, Morgan B., Charles, Julia F., Duryea, Jeffrey, Lehoczky, Jessica A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727699/ https://www.ncbi.nlm.nih.gov/pubmed/36417876 http://dx.doi.org/10.1016/j.celrep.2022.111701 |
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