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The Impact of Cytogenetic Aberrations in the Clonal Evolution of Chronic Myeloid Leukemia: A Single-Center Experience Among 450 Turkish Patients (Cohort Study)

OBJECTIVE: Chronic myeloid leukemia (CML) is a clonal hematologic disorder characterized by t(9;22) translocation, in which cytogenetic aberrations can occur in Ph(+) and (-) clones. These aberrations develop due to clonal evolution as well as treatment and they have prognostic significance. They ar...

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Detalles Bibliográficos
Autores principales: Işık, Sevgi, Günden, Gülçin, Üsküdar Teke, Hava, Akay, Olga Meltem, Oğuz Davutoğlu, Nur, Aslan, Vahap, Karagülle, Mustafa, Özen, Hülya, Çilingir, Oğuz, Artan, Sevilhan, Durak Aras, Beyhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727720/
https://www.ncbi.nlm.nih.gov/pubmed/36199265
http://dx.doi.org/10.4274/tjh.galenos.2022.2022.0045