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Bioactive 2-pyridone-containing heterocycle syntheses using multicomponent reactions

2-Pyridone-containing heterocycles are considered privileged scaffolds in drug discovery due to their behavior as hydrogen bond donors and/or acceptors and nonpeptidic mimics, and remarkable physicochemical properties such as metabolic stability, solubility in water, and lipophilicity. This review p...

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Detalles Bibliográficos
Autores principales: Hurtado-Rodríguez, Diana, Salinas-Torres, Angélica, Rojas, Hugo, Becerra, Diana, Castillo, Juan-Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727751/
https://www.ncbi.nlm.nih.gov/pubmed/36540221
http://dx.doi.org/10.1039/d2ra07056a