SARS-CoV-2 Envelope-mediated Golgi pH dysregulation interferes with ERAAP retention in cells

Endoplasmic reticulum (ER) aminopeptidase associated with antigen processing (ERAAP) trims peptide precursors in the ER for presentation by major histocompatibility (MHC)-I molecules to surveying CD8(+) T-cells. This function allows ERAAP to regulate the nature and quality of the peptide repertoire...

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Detalles Bibliográficos
Autores principales: Vargas-Zapata, Valerie, Geiger, Kristina M., Tran, Dan, Ma, Jessica, Mao, Xiaowen, Puschnik, Andreas S., Coscoy, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727756/
https://www.ncbi.nlm.nih.gov/pubmed/36482965
http://dx.doi.org/10.1101/2022.11.29.518257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727756/
https://www.ncbi.nlm.nih.gov/pubmed/36482965
http://dx.doi.org/10.1101/2022.11.29.518257

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