Human neutralizing antibodies to cold linear epitopes and to subdomain 1 of SARS-CoV-2

Emergence of SARS-CoV-2 variants diminishes the efficacy of vaccines and antiviral monoclonal antibodies. Continued development of immunotherapies and vaccine immunogens resilient to viral evolution is therefore necessary. Using coldspot-guided antibody discovery, a screening approach that focuses o...

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Detalles Bibliográficos
Autores principales: Bianchini, Filippo, Crivelli, Virginia, Abernathy, Morgan E., Guerra, Concetta, Palus, Martin, Muri, Jonathan, Marcotte, Harold, Piralla, Antonio, Pedotti, Mattia, De Gasparo, Raoul, Simonelli, Luca, Matkovic, Milos, Toscano, Chiara, Biggiogero, Maira, Calvaruso, Veronica, Svoboda, Pavel, Rincón, Tomás Cervantes, Fava, Tommaso, Podešvová, Lucie, Shanbhag, Akanksha A., Celoria, Andrea, Sgrignani, Jacopo, Stefanik, Michal, Hönig, Vaclav, Pranclova, Veronika, Michalcikova, Tereza, Prochazka, Jan, Guerrini, Giuditta, Mehn, Dora, Ciabattini, Annalisa, Abolhassani, Hassan, Jarrossay, David, Uguccioni, Mariagrazia, Medaglini, Donata, Pan-Hammarström, Qiang, Calzolai, Luigi, Fernandez, Daniel, Baldanti, Fausto, Franzetti-Pellanda, Alessandra, Garzoni, Christian, Sedlacek, Radislav, Ruzek, Daniel, Varani, Luca, Cavalli, Andrea, Barnes, Christopher O., Robbiani, Davide F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727766/
https://www.ncbi.nlm.nih.gov/pubmed/36482967
http://dx.doi.org/10.1101/2022.11.24.515932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727766/
https://www.ncbi.nlm.nih.gov/pubmed/36482967
http://dx.doi.org/10.1101/2022.11.24.515932

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