Fcγ receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2

Emerging SARS-CoV-2 variants with antigenic changes in the spike protein are neutralized less efficiently by serum antibodies elicited by legacy vaccines against the ancestral Wuhan-1 virus. Nonetheless, these vaccines, including mRNA-1273 and BNT162b2, retained their ability to protect against seve...

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Detalles Bibliográficos
Autores principales: Mackin, Samantha R., Desai, Pritesh, Whitener, Bradley M., Karl, Courtney E., Liu, Meizi, Baric, Ralph S., Edwards, Darin K., Chicz, Taras M., McNamara, Ryan P., Alter, Galit, Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727771/
https://www.ncbi.nlm.nih.gov/pubmed/36482975
http://dx.doi.org/10.1101/2022.11.27.518117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727771/
https://www.ncbi.nlm.nih.gov/pubmed/36482975
http://dx.doi.org/10.1101/2022.11.27.518117

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