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A perinuclear calcium compartment regulates cardiac myocyte hypertrophy

The pleiotropic Ca(2+)/calmodulin-dependent phosphatase calcineurin is a key regulator of pathological cardiac myocyte hypertrophy. The selective activation of hypertrophic calcineurin signaling under stress conditions has been attributed to compartmentation of Ca(2+) signaling in cardiac myocytes....

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Detalles Bibliográficos
Autores principales: Turcotte, Moriah Gildart, Thakur, Hrishikesh, Kapiloff, Michael S., Dodge-Kafka, Kimberly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727780/
https://www.ncbi.nlm.nih.gov/pubmed/35952391
http://dx.doi.org/10.1016/j.yjmcc.2022.07.007