Synergy between inhibitors of two mitotic spindle assembly motors undermines an adaptive response

Mitosis is the cellular process that ensures accurate segregation of the cell’s genetic material into two daughter cells. Mitosis is often deregulated in cancer; thus drugs that target mitosis-specific proteins represent attractive targets for anticancer therapy. Numerous inhibitors have been develo...

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Detalles Bibliográficos
Autores principales: Solon, April L., Zaniewski, Taylor M., O’Brien, Patrick, Clasby, Martin, Hancock, William O., Ohi, Ryoma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727797/
https://www.ncbi.nlm.nih.gov/pubmed/36200902
http://dx.doi.org/10.1091/mbc.E22-06-0225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727797/
https://www.ncbi.nlm.nih.gov/pubmed/36200902
http://dx.doi.org/10.1091/mbc.E22-06-0225

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