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Synergy between inhibitors of two mitotic spindle assembly motors undermines an adaptive response
Mitosis is the cellular process that ensures accurate segregation of the cell’s genetic material into two daughter cells. Mitosis is often deregulated in cancer; thus drugs that target mitosis-specific proteins represent attractive targets for anticancer therapy. Numerous inhibitors have been develo...
Autores principales: | Solon, April L., Zaniewski, Taylor M., O’Brien, Patrick, Clasby, Martin, Hancock, William O., Ohi, Ryoma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727797/ https://www.ncbi.nlm.nih.gov/pubmed/36200902 http://dx.doi.org/10.1091/mbc.E22-06-0225 |
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