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F-actin organization and target constriction during primary macrophage phagocytosis is balanced by competing activity of myosin-I and myosin-II

Phagocytosis requires rapid remodeling of the actin cytoskeleton for extension of membrane protrusions and force generation to ultimately drive the engulfment of targets. The detailed mechanisms of phagocytosis have almost exclusively been studied in immortalized cell lines. Here, we make use of hig...

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Detalles Bibliográficos
Autores principales: Barger, Sarah R., Vorselen, Daan, Gauthier, Nils C., Theriot, Julie A., Krendel, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727803/
https://www.ncbi.nlm.nih.gov/pubmed/36129777
http://dx.doi.org/10.1091/mbc.E22-06-0210