Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice

BACKGROUND: In mice, liver fibrosis is the most serious pathologic change during Schistosoma japonicum (S. japonicum) infection. Schistosomiasis is mainly characterized by schistosome egg-induced granulomatous fibrosis. Hepatic stellate cells (HSCs) are mainly responsible for the net accumulation of...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Ping, Ma, Huihui, Cao, Yun, Zhan, Tingzheng, Zhang, Tingting, Wang, Xinyi, Zhang, Yanan, Xu, Jing, Xia, Chaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727849/
https://www.ncbi.nlm.nih.gov/pubmed/36474240
http://dx.doi.org/10.1186/s13071-022-05584-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727849/
https://www.ncbi.nlm.nih.gov/pubmed/36474240
http://dx.doi.org/10.1186/s13071-022-05584-1

Ejemplares similares