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Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice

BACKGROUND: In mice, liver fibrosis is the most serious pathologic change during Schistosoma japonicum (S. japonicum) infection. Schistosomiasis is mainly characterized by schistosome egg-induced granulomatous fibrosis. Hepatic stellate cells (HSCs) are mainly responsible for the net accumulation of...

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Detalles Bibliográficos
Autores principales:	Huang, Ping, Ma, Huihui, Cao, Yun, Zhan, Tingzheng, Zhang, Tingting, Wang, Xinyi, Zhang, Yanan, Xu, Jing, Xia, Chaoming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727849/ https://www.ncbi.nlm.nih.gov/pubmed/36474240 http://dx.doi.org/10.1186/s13071-022-05584-1

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